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Alzheimer’s disease is like two deaths, said Stephanie Griffin, whose father died of the brain disease in 2015. “It’s horrific,” she said. “First, you watch them lose the ability to talk, to think, to do any of the things they used to do. And then, to see them pass because of it? It’s just … […]

A vast database of cancer genomics knowledge started by Washington University scientists has been named a Global Core Biodata Resource by the Global Biodata Coalition. Led by twin brothers Malachi Griffith, PhD, and Obi Griffith, PhD, both associate professors of medicine, the CIViC “knowledgebase” helps match genetic mutations driving a patient’s cancer growth with possible treatments that target those mutations.

Learning how to use a new set of tools can be challenging, especially when it involves computing technology on which you’ve never been formally trained. Compounding the problem, navigating documentation resources can be a bit hit-and-miss when there is so much to learn, and what you need to learn depends on what you’re trying to […]

NIH study shows genotype-first approach uncovers new links to genetic conditions. National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care. This approach contrasts with the typical phenotype-first approach to clinical research, which starts with clinical findings.

Dr. Christina Gurnett talked about the Institute of Clinical and Translational Sciences Precision Health function, including efforts to integrate of genomic and electronic health record data, engage community and research participants through return of research results, and her own basic science research developing methods to quantify the functional effects of thousands of gene variants using […]