Dr. Cooper, Is a Professor of Pediatrics in Pediatric Rheumatology/Immunology. Her laboratory is focused on mechanisms of immune cell control, including regulation of natural killer cell activation and molecular mechanisms driving pediatric immune-mediated disease. Current work in her laboratory is focused on understanding how metabolic pathways regulate NK cell functional responses and on the origins of pediatric immune dysregulation. Her lab uses genomic sequencing to identify genetic causes of pediatric disease to better understand these diseases using in vitro and in vivo models. Dr. Cooper is the Director of the Clinical Immunology program and the Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies at St. Louis Children’s Hospital.